The development of ballistic missiles, first used by Germany toward the end of World War II, paved the way for the launch vehicles that would fuel a space race between the Soviet Union and the United States. The space race was then followed by an era of space cooperation, highlighted by the International Space Station.
Human space exploration helps to address fundamental questions about our place in the Universe and the history of our solar system. From Yuri Gagarin to the first man on the Moon and the robot that landed on a comet, we look at 10 key dates in space exploration.
Moscow launches the first satellite, Sputnik 1, on October 4, 1957, ushering in the Cold War tussle for the cosmos.
The beach ball-sized aluminium sphere takes 98 minutes to orbit the Earth and sends back the first message from space, simple "beep-beep-beep" radio signals.
A month later Sputnik 2 carries the first living being to fully orbit the Earth, a small street dog called Laika. She dies after a few hours.
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On April 12, 1961 Soviet cosmonaut Yuri Gagarin becomes the first man in space, completing a single, 108-minute orbit aboard Vostok-1.
Twenty-three days later Alan Shepard becomes the first American in space when he makes a 15-minute trip.
On June 16, 1963 cosmonaut Valentina Tereshkova becomes the first woman in space.
It takes a full 40 years for the old Cold War rivals to be joined in space by a third country, when China sends up Yang Liwei onboard Earth orbiter Shenzhou 5.
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The Soviet Union launches the first orbital space station, Salyut 1, on April 19, 1971.
Another Russian space station, Mir, follows. It is brought back to Earth in 2001 after 15 years in orbit.
Construction of the still-operating International Space Station (ISS) starts in 1998. The biggest man-made structure in space, it orbits Earth 16 times a day.
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US spacecraft Viking 1 becomes the first to successfully land on Mars on July 20, 1976 and sends back images of the Red Planet.
The robot Opportunity explored Mars between 2004 and 2018, with NASA's Curiosity Rover still active there.
About 40 missions are sent to Mars, more than half of which fail.
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The US space shuttle Columbia, the first reusable manned spacecraft, makes its first voyage on April 12, 1981.
It is followed by Challenger, Discovery, Atlantis and Endeavour, which serve the ISS until the shuttle programme winds up in 2011.
The US has since depended on Russia to transport its astronauts to the ISS.
Two US shuttles were destroyed in flight, with the loss of 14 astronauts: Challenger in 1986 and Columbia in 2003.
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On April 28, 2001 Italian American multi-millionaire Dennis Tito, 60, becomes the world's first space tourist. He pays Russia $20 million to stay on the ISS for eight days.
In all, seven space tourists have taken Russian flights to the ISS.
The US company SpaceX is planning to launch its first space tourism mission at the end of 2021.
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SpaceX becomes the first private firm to successfully launch a rocket into the Earth's orbit in September 2008.
Its Dragon cargo ship becomes the first commercial spacecraft to visit the ISS in May 2012, on a mission for NASA.
Since then, SpaceX has conquered the satellite launch market with its Falcon 9.
After flights in 2020, SpaceX has planned two other manned launches for NASA to the ISS in 2021, including one which will lift off from Florida on April 22 with French, American and Japanese astronauts.
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The European Space Agency places a small robot, Philae, on a comet more than 500 million kilometres from Earth on November 12, 2014. The first comet lander is part of a mission aiming to explore the origins of the Solar System.
The manmade object that is furthest away from the Earth is the unmanned US spaceship Voyager 1, launched in 1977 and still travelling.
In August 2012 it made it into interstellar space, about 13 billion miles from Earth.
(Photograph:AFP)